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2 article(s) from Docter, Dominic

Protein corona – from molecular adsorption to physiological complexity

Lennart Treuel,
Dominic Docter,
Michael Maskos and
Roland H. Stauber

Beilstein J. Nanotechnol. 2015, 6, 857–873, doi:10.3762/bjnano.6.88

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Figure 1: (a): Relation between the collision efficiency regarding the formation of agglomerates in a destabi...

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Figure 2: (a): Schematic representation of the dimerization redox equilibrium between cystein and cystin. (b)...

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Figure 3: Human serum albumin (HSA, PDB code: 1UOR) represented as space-filling models, colored to indicate ...

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Figure 4: Binding curves as determined by fluorescence correlation spectroscopy and schematic representations...

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Figure 5: Composition of protein coronae around SiNPs of different sizes as identified by quantitative mass s...

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Figure 6: Tenzer et al. [10] revealed in a correlation analysis distinct kinetic protein-binding modalities durin...

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Figure 7: Fluorescence microscopy images (a–d) of the cellular uptake of DHLA-QDs by HeLa cells. Cells were i...

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Review

Published 30 Mar 2015

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The protein corona protects against size- and dose-dependent toxicity of amorphous silica nanoparticles

Dominic Docter,
Christoph Bantz,
Dana Westmeier,
Hajo J. Galla,
Qiangbin Wang,
James C. Kirkpatrick,
Peter Nielsen,
Michael Maskos and
Roland H. Stauber

Beilstein J. Nanotechnol. 2014, 5, 1380–1392, doi:10.3762/bjnano.5.151

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Figure 1: Transmission electron microscopy (TEM) images of representative ASP used in the study. Scale bar = ...

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Figure 2: Microscopy-based assessment of cell vitality by analyzing ASP-induced morphological changes. (A/B) ...

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Figure 3: Impact of ASP30 on the cellular metabolic activity. (A/B/C) Caco-2 cells were incubated with the in...

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Figure 4: Automated microscopy to analyze the impact of exposure to ASP30 on the cell viability. Caco-2 cells...

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Figure 5: Quantification of the impact of ASP30 on the cell viability. Determination of the ratio of the aver...

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Figure 6: The protein corona ameliorates ASP-induced toxicity in GI-tract models. (A/B) Caco-2 cells or HT-29...

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Figure 7: Uptake of fluorescently labeled ASPs. (A/B) Automated microscopy to quantify time-dependent cellula...

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Figure 8: SDS-PAGE analysis to demonstrate the efficient formation of a protein corona around ASP. The indica...

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Full Research Paper

Published 27 Aug 2014

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